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Which of the following is not a valid reason for expelling air from a peel pouch before sealing?

  1. To prevent the formation of air pockets

  2. To ensure proper sterilant penetration

  3. Trapped air will prevent the external indicator from changing color

  4. To maintain the integrity of the packaging seal

The correct answer is: Trapped air will prevent the external indicator from changing color

Expelling air from a peel pouch before sealing is essential to ensure proper sterilization by allowing the sterilant to penetrate the contents effectively. Removing air pockets helps to prevent the potential for incomplete sterilization due to trapped air hindering the sterilant's ability to reach all surfaces. Additionally, expelling air also aids in maintaining the integrity of the packaging seal, reducing the risk of contamination post-sterilization. Option C, stating that trapped air will prevent the external indicator from changing color, is not a valid reason for expelling air from a peel pouch. While an external indicator changing color is crucial for indicating the completion of the sterilization process, expelling air is primarily focused on sterilization effectiveness and packaging integrity, rather than the indicator's function.